Which agent is a dual GIP and GLP-1 receptor agonist?

Which agent is a dual GIP and GLP-1 receptor agonist?

• A. Semaglutide
• B. Exenatide
• C. Tirzepatide
• D. Liraglutide

Answer: (C)

The question is testing your ability to recognize a drug that activates more than one incretin receptor. Incretins like GIP and GLP-1 promote insulin release in a glucose-dependent manner, but each receptor’s activation brings somewhat different effects on glucose control and weight. Tirzepatide is designed to activate both GIP and GLP-1 receptors, giving a dual mechanism that can lead to stronger glycemic control and more weight loss in practice. The other agents listed are GLP-1 receptor agonists only, meaning they stimulate just the GLP-1 receptor and do not provide the additional GIP receptor activity. That makes tirzepatide the correct choice.

The question is testing your ability to recognize a drug that activates more than one incretin receptor. Incretins like GIP and GLP-1 promote insulin release in a glucose-dependent manner, but each receptor’s activation brings somewhat different effects on glucose control and weight.

Tirzepatide is designed to activate both GIP and GLP-1 receptors, giving a dual mechanism that can lead to stronger glycemic control and more weight loss in practice. The other agents listed are GLP-1 receptor agonists only, meaning they stimulate just the GLP-1 receptor and do not provide the additional GIP receptor activity. That makes tirzepatide the correct choice.