DPP-4 inhibitors are commonly referred to by which suffix?

DPP-4 inhibitors are commonly referred to by which suffix?

• A. -gliptins
• B. -glitazones
• C. -formin
• D. -tide

Answer: (A)

DPP-4 inhibitors are identified by the suffix -gliptins. This naming signal helps you recognize the drug class just from the name: sitagliptin, saxagliptin, linagliptin, and alogliptin are all examples of DPP-4 inhibitors. The mechanism is to inhibit the enzyme dipeptidyl peptidase-4, which slows the breakdown of incretin hormones, thereby enhancing glucose-dependent insulin secretion. The other suffixes correspond to different diabetes drug classes: -glitazones are thiazolidinediones, -formin is metformin, and -tide is used for peptide-based drugs like GLP-1 receptor agonists.

DPP-4 inhibitors are identified by the suffix -gliptins. This naming signal helps you recognize the drug class just from the name: sitagliptin, saxagliptin, linagliptin, and alogliptin are all examples of DPP-4 inhibitors. The mechanism is to inhibit the enzyme dipeptidyl peptidase-4, which slows the breakdown of incretin hormones, thereby enhancing glucose-dependent insulin secretion. The other suffixes correspond to different diabetes drug classes: -glitazones are thiazolidinediones, -formin is metformin, and -tide is used for peptide-based drugs like GLP-1 receptor agonists.